OpenClaw a Few Months in: Honeymoon period, Cutoff from Claude Max, OpenAI setup, and Perhaps Migrating to Hermes

March 2026: OpenClaw Setup and honeymoon period In March 2026 I set up a local OpenClaw running on a Mac Mini I procured with that purpose in mind. Mid-March I had the OpenClaw, nicknamed “Nova” write about its setup. End of March, I wrote an exuberant review of my workflow and walking through a usecase, Read More …

Analyzing a Genetic Variant of Unknown Significance Part 2: Driving an Amazon GPU from Claude Code

In Part 1: Analyzing a Genetic Variant of “Unknown Significance: a case study of Science-ing in the agentic era I went over my analysis of my personal genetic variant, using Claude Code, Evo 2 (the NVIDIA hosted version), and comparing with various variant pathogenicity predictors. Part 1 technique recap: Score based on short window before Read More …

The Last Generation of Programmers – the first generation of builders

I spent twenty years acquiring a skill set that took a lifetime to build and that no one will ever need to compile again. How I almost missed it I don’t have the stereotypical programmer’s origin story. No disassembling computers at age seven, no BASIC programs typed into the family TV. My path to programming Read More …

Bridging the Great Stagnation: Why Taking an Extra Decade to Master the Fundamentals Matters

In the 1800s, educated elites were expected to be proficient in Latin, Greek, classical literature, religious knowledge, moral philosophy, public speaking, writing, basic arithmetic, geometry, natural philosophy (covering fundamental physics, astronomy, and biology), music, art, poetry, classical and national history, geography, French, and social graces. Physical activities like horseback riding, rowing, and fencing were also Read More …

Machine Learning and Satellite Imagery

Back in the spring, I had some fun doing experimentation around machine learning models for labelling satellite imagery with atmospheric conditions and various classes of land cover/land. You can check out my work in an open source Kaggle notebook. For this I trained on the data provided in the Planet Kaggle competition, Understanding the Amazon Read More …

5-qubit quantum computing simulator

Since IBM released access to its 5-qubit quantum computer, with accompanying tutorial and ability to simulate and program it easily (via a graphical language that spits out a simple code for archival along with results), I’ve been kind of obsessed. As I worked my way through the tutorials in IBM’s simulator, for my own benefit Read More …

When Antarctica Just Isn't Cold Enough: South Pole Telescope (SPT) Fridge Cycle

As you might have heard on my website, my newsletter, my Twitter, or, if we’re colleagues at Caltech, at work, I am currently working on the South Pole Telescope (SPT) onsite at the South Pole in Antarctica for January-November 2016 (I am employed by the University of Chicago). I have taken a sabbatical from my NSF Astronomy Read More …

Finding earth like planets from the comfort of our own planet

Gravitational lensing results from the fact that General Relativity describes our universe: mass bends light and can function in effect like a lens, bending light in ways that can be used to infer the mass distribution itself. Gravitational microlensing is due to this same effect, but refers to the detection of objects which are of Read More …

The Game of Life-simple rules, complex behavior

Here’s a video introduction to the Game of Life Historically, one of the pioneers of computer science John von Neumann was interested in finding machines which could reproduce themselves. He developed an abstraction allowing him to mathematically model his work on a computational grid. A mathematician John Conway took up and simplified his work publishing Read More …